PIF1 family DNA helicases suppress R-loop mediated genome instability at tRNA genes

Phong Lan Thao Tran; Thomas J. Pohl; Chi-Fu Chen; Angela Chan; Sebastian Pott; Virginia A. Zakian

doi:10.1038/ncomms15025

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JOURNAL ARTICLE

PIF1 family DNA helicases suppress R-loop mediated genome instability at tRNA genes

Phong Lan Thao Tran Thomas J. Pohl Chi-Fu Chen Angela Chan Sebastian Pott Virginia A. Zakian

Year: 2017 Journal: Nature Communications Vol: 8 (1)Pages: 15025-15025 Publisher: Nature Portfolio

DOI: 10.1038/ncomms15025

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Keywords:

Biology Helicase Replication protein A DNA replication DNA Genome instability DNA repair DNA damage Genetics Gene Cell biology Molecular biology DNA-binding protein Transcription factor RNA

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Topics

DNA Repair Mechanisms

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

RNA modifications and cancer

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Genomics and Chromatin Dynamics

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

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