Complex-Valued Neural Networks

Abstract

In this chapter, the authors will try to go through the problem of learning the complex-valued neural networks (CVNNs) using particle swarm optimization (PSO); which is one of the open topics in the machine learning society. Quantitative structure-activity relationship (QSAR) modelling is one of the well developed areas in drug development through computational chemistry. This relationship between molecular structure and change in biological activity is center of focus for QSAR modelling. Machine learning algorithms are important tools for QSAR analysis, as a result, they are integrated into the drug production process. Predicting the real-valued drug activity problem is modelled by the CVNN and is learned by a new strategy based on PSO. The trained CVNNs are tested on two drug sets as a real world bench-mark problem. The results show that the prediction and generalization abilities of CVNNs is superior in comparison to the conventional real-valued neural networks (RVNNs). Moreover, convergence of CVNNs is much faster than that of RVNNs in most of the cases.