This work expands our knowledge about optimal programs of pathway control. Optimal targets of pathway control strongly depend on the speed at which proteins can be synthesized. Moreover, post-translational regulation such as allosteric regulation allows to strongly reduce the number of transcriptional regulatory interactions required to control a metabolic pathway across different pathway topologies.
J. Blasco MelguizoRicardo Ruíz‐VillaverdeI. Sánchez Rodríguez
Juliana Pérez-BernalAlejandro Castellanos-AngaritaEdwin Bendek
S GoldhaberL VisaniDe RosaMS GoldhaberE FerrariA ImbertT ChevalierA MihoubiP MorandM Baudouy