Accelerated magnetic resonance spectroscopy with Vandermonde factorization

Abstract

Multi-dimensional magnetic resonance spectroscopy is an important tool for studying molecular structures, interactions and dynamics in bio-engineering. The data acquisition time, however, is relatively long and non-uniform sampling can be applied to reduce this time. To obtain the full spectrum,a reconstruction method with Vandermonde factorization is proposed. This method explores the general signal property in magnetic resonance spectroscopy: Its time domain signal is approximated by a sum of a few exponentials. Results on synthetic and realistic data show that the new approach can achieve faithful spectrum reconstruction and outperforms state-of-the-art low rank Hankel matrix method.