Differential Pulse Polarography and Adsorptive Stripping Voltammetric Determination of Uric Acid

Abstract

Chemistry Department, Faculty of Science, Atsiut, Egypt Chemistry Department, Faculty of Science, Aswan, Egypt Manuscript received 15 June 1992, accepted 1 September 1992 The complex formation between uric acid and zinc, cadmium and lead ions bas been investigated using differential pulse polarography in 0.01 M NaNO₃. The complexes formed by Cd^II and Pb^lI with uric acid have the stoichiometry of 1 : 2. Zn^ll does not give any indication of complexation with uric acid. A sensitive voltammetric method is developed for the quantitative determination of uric acid based on controlled adsorptive preconcentration of uric acid on the hanging mercury drop electrode. The modes used are direct current stripping voltammetry and differential pulse stripping voltammetry. The adsorptive stripping response was evaluated with respect to preconcentration time and potential, concentration dependence and composition of supporting electrolyte.