Synthesis and Characterization of Fe3O4 Magnetic Nanoparticles Coated with Carboxymethyl Chitosan Grafted Sodium Methacrylate

Abstract

N-sodium acrylate-O-carboxymethyl chitosan [CMCH-g-PAA(Na)] bound Fe3O4 nanoparticles were developed as a novel magnetic nanoparticles with an ionic structure that can be potentially used in many fields. CMCH-g-PAA (Na) was obtained by grafting of sodium polyacrylate on O-carboxymethyl chitosan, which is an amphiphilic polyelectrolyte with the biocompatibility and biodegradability properties. According to the great interest for improving the stability of Fe3O4 nanoparticles, CMCH-g-PAA (Na) was used as a stabilizer to prepare a well dispersed suspension of magnetic nanoparticle According to the results,the presence of CMCH-g-PAA(Na) could eliminate agglomeration of magnetic nanoparticles without destroying the superparamagnetic properties