Non‐enzymatic Amperometric Glucose Sensor Based on Copper Nanowires Decorated Reduced Graphene Oxide

Abstract

Abstract A nanocomposite consisting of one‐dimensional copper nanowires and two‐dimensional reduced graphene oxide nanosheets (CuNWs/rGO) was synthesized by a simple one‐step wet‐chemical synthetic process. The Cu NWs anchored onto the rGO nanosheets with wrinkles and folds had a smooth surface. The CuNWs/rGO hybrids exhibited excellent electrocatalytic activity toward glucose oxidation due to the superior conductivity along one‐dimensional direction and excellent catalytic activity of Cu NWs and rapid electron transfer in the two‐dimensional rGO sheets. A wide linear range up to 11 mM, high sensitivity (1625 µA/(mM ⋅ cm 2 )), low detection limit (0.2 µM) and fast response (<2 s) to glucose oxidation were obtained under a working potential of 0.58 V for the hybrid with optimized Cu/rGO mass ratio in the alkaline solution. Furthermore, the CuNWs/rGO composites displayed high selectivity to glucose and resistance against poisoning by commonly interfering species such as ascorbic acid, dopamine, uric acid, acetamidophenol and some carbohydrates. The CuNWs/rGO hybrids with good reproducibility, stability and poisoning resistance to chloride ions were therefore promising for the potential application as non‐enzymatic amperometric glucose sensors with improved electrochemical performances.