Lipid peroxidation and antioxidant enzymes

Abstract

The role of reactive oxygen species (ROS) in the pathologic and physiologic effects on health has been emphasized in recent years. Production of ROS by mitochondria is generally thought to be the main cause of oxidative stres (OS). ROS are neutralized by various antioxidant defense mechanisms such as catalase, superoxide dismutase and glutathione peroxidase, vitamin C, vitamin E, vitamin A, pyruvate, glutathione, taurine and hypotaurine. Biomarkers of oxidative damage associated with human diseases could be used to diagnose and manage the diseases.