EPM1 is characterized by widespread alterations in subcortical WM, the thalamocortical system, and the cerebellum, which result in axonal degeneration and WM loss. These data suggest that motor disturbances and other symptoms in patients with EPM1 involve not only the cortical system but also the thalamocortical system and cerebellum.
Johana ContrerasMery Rodríguez Parra
Antoni Arasanz MayolasBegoña Ladrón de Guevara Pascual
Alexánder Rodríguez BustamanteJenny Josefina Vicuña RomeroJohanna Jazmín Zapata Posada
Arbués, ElenaNaval, Concepción