Application of peptide-based fluorescent probes in protein detection

Abstract

Peptide-based fluorescent probe as a kind of fluorescent probes has been widely applicated in tracing protein detection. The structure and detection principle of three main types of peptide-based fluorescent probes including mono-labelled peptide probe, dual-labelled peptide probe and composite peptide probe conjugated with other materials, as well as their applications in qualitative or quantitative protein detection and enzyme activities evaluation were reviewed. The future devlopement of peptide-based fluorescent probes was highlighted.