Electrochemical Sensor for Ultrasensitive Determination of Bisphenol A based on Gold Nanoparticles/β-cyclodextrin Functionalized Reduced Graphene Oxide Nanocomposite

Abstract

In this work, an electrochemical sensor based on a β-cyclodextrin functionalized reduced graphene oxide/gold nanoparticles (β-CD/RGO/Au) composite modified glassy carbon electrode (GCE) was proposed for the ultrasensitive detection of bisphenol A (BPA).The β-CD/RGO/Au nanocomposite was synthesized by a microwave heating method followed by an electrodeposition process.The prepared nanocomposite was carefully characterized by FTIR, Raman spectroscopy, UV-vis spectroscopy, SEM, EDX and XRD.The electrocatalytic oxidation of BPA on the modified GCE was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV).The results showed that the β-CD/RGO/Au modified GCE could effectively enhance the electrochemical detection performance towards oxidation of BPA due to the synergetic effects of RGO and Au NPs with supramolecular recognition capability of β-CD.The proposed sensor exhibited excellent linear relationship between the detection current and BPA concentration in the range from 0.01 to 50 μM.The detection limit was estimated as 0.003 μM (S/N = 3).Moreover, the proposed BPA sensor has also been successfully used for determining BPA in various real samples.