Recyclable graphene-supported palladium nanocomposites for Suzuki coupling reaction

Abstract

Abstract In the search of new materials for developing clean catalytic organic reactions, our team engineered graphene based palladium (Pd) nanocomposites and tested them as catalysts for ionic liquid mediated Suzuki cross coupling reaction. The effects of various reaction parameters, such as solvent, base, time and temperature, were investigated for the Suzuki reaction. The optimized protocol was applied to a wide range of substituted aryl/hetroaryl halides along with various aryl boronic acids and afforded the corresponding reaction products in good to excellent yield. The proposed Pd/reduced graphene oxide (rGO) catalyzed Suzuki reaction protocol was also exploited for the synthesis of unique indazole derivatives. The developed catalytic system circumvents the use of phosphine ligands, with an added advantage of easy Pd catalyst recovery up to eight times.