Platinum nanoparticles-single-walled carbon nanotubes hybrid based chemiresistive sensor array for myoglobin detection

Abstract

We examined the potential of platinum nanoparticles (PtNP) modified single-walled carbon nanotube (SWNT) hybrid chemiresistive sensor for detection of antigen myoglobin (Mb) in phosphate buffer saline. Protein antibody, Ab-Mb, was covalently immobilized through site specific binding on PtNP attached over SWNT. A concentration-dependent change in the source–drain current of the hybrid device was observed in the range of 0.1–1000 ng ml−1. The hybrid device response fitted well with the Hill–Langmuir equation with a maximum response of 111.14% and low dissociation constant value (Kd = 19.98 ng ml−1), indicating high protein antigen binding affinity at hybrid nanostructure.