RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis
Jae‐Kyung LeeGeorge T. KannarkatJaegwon ChungHyun Joon LeeKareem L. GrahamMalú G. Tansey
Abstract
These data demonstrate a critical role for RGS10 in mediating autoimmune disease through regulation of T lymphocyte function. This is the first study ever conducted to elucidate the function of RGS10 in effector lymphocytes in the context of EAE. The identification of RGS10 as an important regulator of inflammation might open possibilities for the development of more specific therapies for MS.
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