Morphologies of Multicompartment Micelles formed by Triblock Copolymers

Abstract

Multicompartment micelles are desirable for advanced applications such as drug delivery. Recently, core‐shell‐corona (CSC) and segmented‐worm (SW) micelles formed by ABC triblock terpolymers with three mutually immiscible blocks are observed in experiments. We have performed dissipative particle dynamics simulations to study the effects of molecular architecture, block length and solution concentration on the morphologies of ABC triblock terpolymers. The formation of CSC and SW micelles for linear and miktoarm star ABC terpolymers is confirmed in this work. In addition, we predict that different multicompartment micellar morphologies (e.g. incomplete skin‐layered micelles and segmented worms) can be formed by linear copolymer with different arrangements of the three blocks.