Host‐Guest Interaction between Herbicide Oxadiargyl and Hydroxypropyl‐β‐Cyclodextrin

Abstract

In the face of a growing human population and increased urbanization, the demand for pesticides will simply rise. Farmers must escalate yields on increasingly fewer farm acres. However, the risks of pesticides, whether real or perceived, may force changes in the way these chemicals are used. Scientists are working toward pest control plans that are environmentally sound, effective, and profitable. In this context the development of new pesticide formulations which may improve application effectiveness, safety, handling, and storage can be pointed out as a solution. As a contribution to the area, the microencapsulation of the herbicide oxadiargyl (OXA) in (2‐hydroxypropyl)‐ β ‐cyclodextrin (HP‐ β ‐CD) was performed. The study was conducted in different aqueous media (ultrapure water and in different pH buffer solutions). In all cases an increment of the oxadiargyl solubility as a function of the HP‐ β ‐CD concentration that has been related to the formation of an inclusion complex was verified. UV‐Vis and NMR experiments allowed concluding that the stoichiometry of the OXA/HP‐ β ‐CD complex formed is 1 : 1. The gathered results can be regarded as an important step for its removal from industrial effluents and/or to increase the stabilizing action, encapsulation, and adsorption in water treatment plants.