JOURNAL ARTICLE

Lapatinib and Obatoclax Kill Breast Cancer Cells through Reactive Oxygen Species-Dependent Endoplasmic Reticulum Stress

Nichola CruickshanksYong TangLaurence BoothHossein A. HamedSteven GrantPaul Dent

Year: 2012 Journal:   Molecular Pharmacology Vol: 82 (6)Pages: 1217-1229   Publisher: American Society for Pharmacology and Experimental Therapeutics
Keywords:
Lapatinib Unfolded protein response Protein kinase A Programmed cell death Autophagy Cancer cell PTEN Cancer research Biology Kinase Cell biology Endoplasmic reticulum Chemistry PI3K/AKT/mTOR pathway Signal transduction Biochemistry Apoptosis Cancer Breast cancer

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39
Cited By
3.74
FWCI (Field Weighted Citation Impact)
46
Refs
0.92
Citation Normalized Percentile
Is in top 1%
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Citation History

Topics

Autophagy in Disease and Therapy
Health Sciences →  Medicine →  Epidemiology
PI3K/AKT/mTOR signaling in cancer
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology
Biochemical and Molecular Research
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology

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