JOURNAL ARTICLE
Endothelial lipase enhances low density lipoprotein binding and cell association in THP-1 macrophages
Year: 2007 Journal: Cardiovascular Research Vol: 76 (3)Pages: 528-538 Publisher: Oxford University Press
Abstract
EL expression promotes the binding and uptake of native and oxidized LDL in THP-1 macrophages in a heparan sulfate proteoglycan-dependent manner, and the LDL receptor was partly responsible for the EL-enhanced uptake of native LDL.
Keywords:
CD36 Foam cell THP1 cell line Chemistry Receptor Cell culture Molecular biology Antibody Lipoprotein LDL receptor Cell Scavenger receptor Biochemistry Biology Cholesterol Immunology
Metrics
13
Cited By
0.77
FWCI (Field Weighted Citation Impact)
47
Refs
0.68
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
Atherosclerosis and Cardiovascular Diseases
Life Sciences → Immunology and Microbiology → Immunology
Lipid metabolism and disorders
Health Sciences → Medicine → Cardiology and Cardiovascular Medicine
Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences → Medicine → Endocrinology, Diabetes and Metabolism
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