WARM ISCHEMIA AND REPERFUSION INJURY IN DIET-INDUCED CANINE FATTY LIVERS
Katsuro TakahashiKenichi HakamadaEishi TotsukaYutaka UmeharaMutsuo Sasaki
Abstract
Damage to hepatocytes and nonparenchymal cells after warm ischemia and reperfusion was thought to be closely related to sinusoidal microcirculatory disturbances in fatty livers. The canine fatty liver model reported here may be useful in studying the pathology of primary nonfunction and in establishing criteria for allowable degrees of fatty change in potential liver grafts.
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