Enzyme-free colorimetric assay of serum uric acid

Raj Kumar Bera; Anakuthil Anoop; C. Retna Raj

doi:10.1039/c1cc13349g

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Enzyme-free colorimetric assay of serum uric acid

Raj Kumar Bera Anakuthil Anoop C. Retna Raj

Year: 2011 Journal: Chemical Communications Vol: 47 (41)Pages: 11498-11498 Publisher: Royal Society of Chemistry

DOI: 10.1039/c1cc13349g

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Abstract

A nonenzymatic method for the selective detection and quantification of serum uric acid (UA) using 2-thiouracil (2-TU) tailored Au nanoparticles is developed. The H-bonding interaction of UA with functionalized Au nanoparticles brings instantaneous visible color change and paves the way for the visible sensing of UA.

Keywords:

Uric acid Chemistry Enzyme Nanoparticle Thiouracil Colorimetry Colorimetric analysis Nuclear chemistry Chromatography Combinatorial chemistry Biochemistry Photochemistry Nanotechnology Materials science Biology

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Molecular Sensors and Ion Detection

Physical Sciences → Chemistry → Spectroscopy

Advanced biosensing and bioanalysis techniques

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Electrochemical sensors and biosensors

Physical Sciences → Engineering → Electrical and Electronic Engineering

Enzyme-free colorimetric assay of serum uric acid

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