JOURNAL ARTICLE
Antihyperglycemic Activity of Helicteres isora Roots in Alloxan-Induced Diabetic Rats
Sama VenkateshG. Dayanand ReddyB. Madhava Reddy
Year: 2003 Journal: Pharmaceutical Biology Vol: 41 (5)Pages: 347-350 Publisher: Taylor & Francis
Abstract
AbstractThe effect of administrating different extracts of Helicteres isora L. (Sterculiaceae) roots on blood glucose levels in normal and alloxan-induced diabetic rats was evaluated in this study. Among the five fractions (aqueous ethanol, chloroform, ethyl acetate, butanol and left over aqueous), the butanol fraction at a dose of 250 mg/kg showed maximum antihyperglycemic activity. The same dose did not cause any hypoglycemic activity in normal rats.
Keywords:
Alloxan Traditional medicine Diabetes mellitus Ethyl acetate Sterculiaceae Ethanol Medicinal plants Chemistry Chloroform Aqueous extract Butanol Pharmacognosy Pharmacology Medicine Biology Endocrinology Biological activity In vitro Biochemistry Botany Chromatography
Metrics
17
Cited By
0.60
FWCI (Field Weighted Citation Impact)
10
Refs
0.68
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
Natural Antidiabetic Agents Studies
Health Sciences → Medicine → Endocrinology, Diabetes and Metabolism
Ziziphus Jujuba Studies and Applications
Life Sciences → Agricultural and Biological Sciences → Food Science
Phytochemistry and biological activities of Ficus species
Life Sciences → Agricultural and Biological Sciences → Plant Science
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