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JOURNAL ARTICLE

Ultrasensitive surface-enhanced Raman scattering detection of alkaline phosphatase

Jian Dong Yuan Li Mingyue Zhang zhang Li Tianyu Yan Weiping Qian

Year: 2014 Journal: Analytical Methods Vol: 6 (22)Pages: 9168-9172 Publisher: Royal Society of Chemistry

DOI: 10.1039/c4ay01885k

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Abstract

In this study, an ultrasensitive surface-enhanced Raman scattering (SERS) detection of alkaline phosphatase (ALP) has been developed, in which nile blue A (NBA) was chosen to replace nitro blue tetrazolium chloride (NBT) in a reactive system of 5-bromo-4-chloro-3-indolyl phosphate (BCIP), NBT, and ALP.

Keywords:

Alkaline phosphatase Raman scattering Chemistry Detection limit Nile blue Phosphate Chloride Raman spectroscopy Nuclear chemistry Chromatography Enzyme Biochemistry Optics Fluorescence Organic chemistry Physics

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Topics

Carbon and Quantum Dots Applications

Physical Sciences → Materials Science → Materials Chemistry

Gold and Silver Nanoparticles Synthesis and Applications

Physical Sciences → Materials Science → Electronic, Optical and Magnetic Materials

Advanced biosensing and bioanalysis techniques

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

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