Clicking dendritic peptides onto single walled carbon nanotubes

Abstract

Here, we demonstrate a straightforward click-chemistry-based approach for the functionalisation of single walled carbon nanotubes with oligo-lysine dendrons. Azide-functionalised nanotubes were reacted with alkyne-focal dendrons using the 1,3 dipolar Cu-catalysed azide alkyne cycloaddition reaction. Peptide dendron functionalised nanotubes showed significantly increased biocompatibility in rat mesenchymal stem cell culture.