Label-free and high-throughput screening of biomolecular interactions

I. Emre Özkumur; J. R. Needham; David A. Bergstein; M. Ruane; Bennett B. Goldberg; M. Selim Ünlü

doi:10.1109/cleo.2008.4550964

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Label-free and high-throughput screening of biomolecular interactions

I. Emre Özkumur J. R. Needham David A. Bergstein M. Ruane Bennett B. Goldberg M. Selim Ünlü

Year: 2008 Pages: 1-2

DOI: 10.1109/cleo.2008.4550964

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Abstract

We present a simple label-free multi-analyte detection technique that is easily scalable for high-throughput screening. We have shown a sensitivity of 20 pg/mm ² and a minimum detectable antibody concentration of 15 ng/ml for a specific antigen.

Keywords:

Scalability Throughput Analyte High-throughput screening Computer science Sensitivity (control systems) Chemistry Combinatorial chemistry Computational biology Chromatography Biology Biochemistry Engineering Database Electronic engineering

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Advanced Biosensing Techniques and Applications

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Molecular Junctions and Nanostructures

Physical Sciences → Engineering → Electrical and Electronic Engineering

Advanced biosensing and bioanalysis techniques

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Label-free and high-throughput screening of biomolecular interactions

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