Quorum Sensing and Quorum Quenching Facebook of Microbial World

Abstract

Dental Plaque is an example of biofilm leading periodontal disease and dental caries. Many Gram-positive and Gram-negative bacteria communicate using small diffusible signal molecules called autoinducers. This process, known as quorum sensing, links cell density the expression of genes as diverse as those associated with virulence fac- tors production of pathogens, bioluminescence, antibiotic production, sporulation of biofilm formation. The interference with these signaling systems, also known as Quorum Quenching, represents a promising strategy tackle bacterial infections. Recent advances have revealed that bacteria are not only limited communicate within their own species but also are capable of listening and broadcasting to unrelated species intercept messages and coerce cohabitants into behavioral modification for increase in cell population and density.