JOURNAL ARTICLE

Cell-based apoptosis assays in oncology drug discovery

John DreweSui Xiong Cai

Year: 2010 Journal:   Expert Opinion on Drug Discovery Vol: 5 (6)Pages: 583-596   Publisher: Taylor & Francis

Abstract

Phenotype proapoptotic screen followed by chemical genetics is useful for anticancer drug research, for the discovery of potential drugs and identification of druggable targets.

Keywords:
Drug discovery Context (archaeology) Computational biology Biology Cell Apoptosis Phenotypic screening Drug Phenotype Bioinformatics Cancer research Pharmacology Genetics Gene

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12
Cited By
0.14
FWCI (Field Weighted Citation Impact)
80
Refs
0.52
Citation Normalized Percentile
Is in top 1%
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Citation History

Topics

Cell death mechanisms and regulation
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology
Cancer therapeutics and mechanisms
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology
Computational Drug Discovery Methods
Physical Sciences →  Computer Science →  Computational Theory and Mathematics
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