Preparation and Characterization of beta-Carotene Encapsulated Chitosan, Oleic Acid Coated Fe3O4 Nanoparticles

Abstract

In this work β-Carotene encapsulated Chitosan, oleic acid coated Fe ₃ O ₄ nanoparticles were prepared by modifying solvent displacement technique. Nanoparticles containing β-carotene were produced by interfacial deposition of the metal oxide/polymer nanocomposite, due to the displacement of acetone from the dispersed phase. Between 20 is used as the stabilizing agent, β-carotene was entrapped in the metal oxide/polymeric matrix. Particles were characterized by X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), UV-Visible spectroscopy (Uv-Vis), optical microscope (OM). Entrapment efficiency was calculated and In-Vitro release study has been done.