JOURNAL ARTICLE

Doxorubicin‐Loaded Magnetic Silk Fibroin Nanoparticles for Targeted Therapy of Multidrug‐Resistant Cancer

Abstract

A strategy to prepare doxorubicin-loaded magnetic silk fibroin nanoparticles is presented. The nanoparticles serve as a nanometer-scale drug-delivery system in the chemotherapy of multidrug-resistant cancer under the guidance of a magnetic field. The magnetic tumor-targeting ability broadens the range of biomedical applications of silk fibroin, and the nanoparticle-assisted preparation strategy is useful for the advancement of other biomacromolecule-based materials.

Keywords:
Fibroin Materials science Magnetic nanoparticles Doxorubicin Nanotechnology Nanoparticle Drug delivery Cancer therapy Nanometre SILK Cancer Chemotherapy Composite material Medicine

Metrics

253
Cited By
8.33
FWCI (Field Weighted Citation Impact)
34
Refs
0.99
Citation Normalized Percentile
Is in top 1%
Is in top 10%

Citation History

Topics

Silk-based biomaterials and applications
Physical Sciences →  Materials Science →  Biomaterials
Nanoparticle-Based Drug Delivery
Physical Sciences →  Materials Science →  Biomaterials
Protease and Inhibitor Mechanisms
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Cancer Research
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