JOURNAL ARTICLE

Random Effects Selection in Linear Mixed Models

Zhen ChenDavid B. Dunson

Year: 2003 Journal:   Biometrics Vol: 59 (4)Pages: 762-769   Publisher: Oxford University Press

Abstract

Summary . We address the important practical problem of how to select the random effects component in a linear mixed model. A hierarchical Bayesian model is used to identify any random effect with zero variance. The proposed approach reparameterizes the mixed model so that functions of the covariance parameters of the random effects distribution are incorporated as regression coefficients on standard normal latent variables. We allow random effects to effectively drop out of the model by choosing mixture priors with point mass at zero for the random effects variances. Due to the reparameterization, the model enjoys a conditionally linear structure that facilitates the use of normal conjugate priors. We demonstrate that posterior computation can proceed via a simple and efficient Markov chain Monte Carlo algorithm. The methods are illustrated using simulated data and real data from a study relating prenatal exposure to polychlorinated biphenyls and psychomotor development of children.

Keywords:
Random effects model Prior probability Markov chain Monte Carlo Mixed model Generalized linear mixed model Mathematics Linear model Gibbs sampling Computer science Bayesian probability Applied mathematics Statistics Algorithm

Metrics

235
Cited By
2.87
FWCI (Field Weighted Citation Impact)
37
Refs
0.91
Citation Normalized Percentile
Is in top 1%
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Citation History

Topics

Statistical Methods and Bayesian Inference
Physical Sciences →  Mathematics →  Statistics and Probability
Statistical Methods and Inference
Physical Sciences →  Mathematics →  Statistics and Probability
Bayesian Methods and Mixture Models
Physical Sciences →  Computer Science →  Artificial Intelligence

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