JOURNAL ARTICLE
Comparative evaluation of two polymerase chain reactions targeting different genomic regions to detect Mycobacterium tuberculosis in sputum
Sathish SankarBiju BalakrishnanB NandagopalKannaki ThangarajuSubapriya Natarajan
Year: 2010 Journal: Indian Journal of Medical Microbiology Vol: 28 (4)Pages: 303-307 Publisher: Elsevier BV
Abstract
The non-nested TRC 4 PCR showed inability for accurate detection of M. tuberculosis in sputum samples. The study concluded that the nPCR targeting IS6110 is superior and more sensitive than TRC 4 PCR.
Keywords:
Sputum Tuberculosis Mycobacterium tuberculosis Nested polymerase chain reaction Medicine Polymerase chain reaction Mycobacterium tuberculosis complex Internal medicine Gold standard (test) Kappa Gastroenterology Pathology Biology Gene
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3
Cited By
0.65
FWCI (Field Weighted Citation Impact)
23
Refs
0.70
Citation Normalized Percentile
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Citation History
Topics
Mycobacterium research and diagnosis
Health Sciences → Medicine → Epidemiology
Tuberculosis Research and Epidemiology
Health Sciences → Medicine → Infectious Diseases
Diagnosis and treatment of tuberculosis
Health Sciences → Medicine → Surgery
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