JOURNAL ARTICLE

Enhanced cellular uptake of aminosilane-coated superparamagnetic iron oxide nanoparticles in mammalian cell lines

Yì WángZhuLeungLeeZhaoWangLaiChao WanChristopher H.K. ChengAnil T. Ahuja

Year: 2012 Journal:   International Journal of Nanomedicine Vol: 7 Pages: 953-953   Publisher: Dove Medical Press

Abstract

Cellular uptake efficiency of SPIO nanoparticles depends on both the cell type and SPIO surface characteristics. Aminosilane surface coating enhanced the cellular uptake efficiency without inducing cytotoxicity in a number of cell lines.

Keywords:
Viability assay Nanoparticle Prussian blue Cell culture Intracellular Biophysics Transmission electron microscopy Flow cytometry Chemistry In vitro Molecular biology Nuclear chemistry Materials science Nanotechnology Biochemistry Biology Electrochemistry

Metrics

141
Cited By
8.96
FWCI (Field Weighted Citation Impact)
59
Refs
0.99
Citation Normalized Percentile
Is in top 1%
Is in top 10%

Citation History

Topics

Nanoparticle-Based Drug Delivery
Physical Sciences →  Materials Science →  Biomaterials
Graphene and Nanomaterials Applications
Physical Sciences →  Engineering →  Biomedical Engineering
Iron Metabolism and Disorders
Health Sciences →  Medicine →  Hematology

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