JOURNAL ARTICLE
Selective G-quadruplex stabilizers: Schiff-base metal complexes with anticancer activity
Alessio TerenziRiccardo BonsignoreAngelo SpinelloCarla GentileAnnamaria MartoranaCosimo DucaniBjörn HögbergAnna Maria AlmericoAntonino LauriaGiampaolo Barone
Year: 2014 Journal: RSC Advances Vol: 4 (63)Pages: 33245-33256 Publisher: Royal Society of Chemistry
Abstract
Molecular dynamics simulations and quantum mechanics/molecular mechanics calculations provided a mechanism for G-quadruplex binding of three transition metal complexes.
Keywords:
Molecular mechanics G-quadruplex Schiff base Molecular dynamics Chemistry Metal Computational chemistry Combinatorial chemistry Stereochemistry DNA Organic chemistry Biochemistry
Metrics
95
Cited By
4.88
FWCI (Field Weighted Citation Impact)
76
Refs
0.96
Citation Normalized Percentile
Is in top 1%
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Citation History
Topics
DNA and Nucleic Acid Chemistry
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
Advanced biosensing and bioanalysis techniques
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
RNA Interference and Gene Delivery
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
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