JOURNAL ARTICLE

Cytotoxic Oleanane Triterpene Saponins from Albizia chinensis

Rui LiuShuang‐Gang MaShi‐Shan YuYue‐Hu PeiSen ZhangXiaoguang ChenJianjun Zhang

Year: 2009 Journal:   Journal of Natural Products Vol: 72 (4)Pages: 632-639   Publisher: American Chemical Society

Abstract

Three new oleanane-type triterpene saponins, albizosides A-C (1-3), were isolated from the stem bark of Albizia chinensis. Their structures were established by 1D and 2D NMR experiments and chemical methods. Compounds 1-3 showed cytotoxic activity against a small panel of human tumor cell lines as well as hemolytic activity against rabbit erythrocytes.

Keywords:
Triterpene Oleanane Pharmacognosy Traditional medicine Saponin Triterpenoid Chemistry Biology Stereochemistry Botany Biological activity Medicine In vitro Biochemistry

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Citation History

Topics

Natural product bioactivities and synthesis
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology
Plant biochemistry and biosynthesis
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology
Sesquiterpenes and Asteraceae Studies
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Cancer Research
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