Fully collaborative guest binding by a double cyclodextrin host

Abstract

A double cyclodextrin host (3b) shows the largest association constant reported for a modified cyclodextrin (Kass.= 2 030 000 mol–1 dm3; with ethyl orange); the greater (×224) degree of association of this guest with (3b) as compared with β-cyclodextrin, demonstrates the full collaboration of the two binding sites.