Association Between Metabolic Syndrome and Liver Histology Among Children With Nonalcoholic Fatty Liver Disease
Heather PattonKatherine P. YatesAynur Ünalp–AridaCynthia BehlingTerry T.‐K. HuangPhilip RosenthalArun J. SanyalJeffrey B. SchwimmerJoel E. Lavine
Abstract
MetS is common among children with NAFLD and is associated with severity of steatosis, hepatocellular ballooning, NAS, NAFLD pattern, and the presence of advanced fibrosis. Individual MetS features, particularly central obesity and insulin resistance, were also associated with severity of NAFLD. MetS features should be considered in children with NAFLD as individually and collectively they help identify children with more advanced disease.
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