JOURNAL ARTICLE

Probe-label-free electrochemical aptasensor based on methylene blue-anchored graphene oxide amplification

Jing Rong ChenXiao Xia JiaoHong Qun LuoNian Bing Li

Year: 2012 Journal:   Journal of Materials Chemistry B Vol: 1 (6)Pages: 861-864   Publisher: Royal Society of Chemistry

Abstract

Two novel probe-label-free electrochemical aptasensors based on methylene blue (MB)-anchored graphene oxide (GO) amplification were developed for thrombin (TB) and ATP detection, taking advantage of the specific binding affinity of the aptamer towards the target and the different affinities of GO for MB, ssDNA, dsDNA, and G-quadruplex.

Keywords:
Methylene blue Aptamer Graphene Electrochemistry Oxide Combinatorial chemistry Nanotechnology Materials science Affinities Chemistry Electrode Molecular biology Stereochemistry Biochemistry Physical chemistry Biology

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51
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2.94
FWCI (Field Weighted Citation Impact)
26
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0.91
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Citation History

Topics

Advanced biosensing and bioanalysis techniques
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology
RNA Interference and Gene Delivery
Life Sciences →  Biochemistry, Genetics and Molecular Biology →  Molecular Biology
Molecular Junctions and Nanostructures
Physical Sciences →  Engineering →  Electrical and Electronic Engineering
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