JOURNAL ARTICLE
Synthesis of nedocromil sodium labelled with tritium, deuterium and carbon‐14
David J. WilkinsonW. J. S. Lockley
Year: 1985 Journal: Journal of Labelled Compounds and Radiopharmaceuticals Vol: 22 (9)Pages: 883-892 Publisher: Wiley
Abstract
Abstract Nedocromil sodium labelled with carbon‐14 has been prepared by a Claisen reaction between diethyl [1,2‐ 14 C]‐ethanedioate and methyl 6‐ethanoyl‐1‐ethyl‐1,4‐dihydro‐7‐hydroxy‐4‐oxo‐8‐propylquinoline‐2‐carboxylate. The 2 H‐ and 3 H‐labelled materials are readily prepared by rhodium(III) chloride catalysed exchange with the appropriate isotopically labelled water.
Keywords:
Chemistry Tritium Deuterium Sodium Carbon-14 Carboxylate Nuclear chemistry Radiochemistry Nedocromil Sodium Carbon fibers Medicinal chemistry Organic chemistry Inorganic chemistry
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16
Cited By
1.46
FWCI (Field Weighted Citation Impact)
4
Refs
0.77
Citation Normalized Percentile
Is in top 1%
Is in top 10%
Citation History
Topics
Chemical Reactions and Isotopes
Life Sciences → Pharmacology, Toxicology and Pharmaceutics → Pharmaceutical Science
Synthesis and Biological Evaluation
Physical Sciences → Chemistry → Organic Chemistry
Chemical Synthesis and Analysis
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
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