JOURNAL ARTICLE

Carrier-free, functionalized drug nanoparticles for targeted drug delivery

Wěi LiYinlong YangChao WangZhuang LiuXiujuan ZhangFeifei AnXiaojun DiaoXiaojun HaoXiaohong Zhang

Year: 2012 Journal:   Chemical Communications Vol: 48 (65)Pages: 8120-8120   Publisher: Royal Society of Chemistry

Abstract

We demonstrate a new concept of carrier-free functionalized drug nanoparticles for targeted drug delivery. It exhibits significantly enhanced drug efficacy to folate receptor-positive cells with high selectivity and a high drug loading content up to more than 78%.

Keywords:
Drug Drug delivery Targeted drug delivery Nanoparticle Pharmacology Selectivity Chemistry Nanotechnology Drug carrier Materials science Medicine Biochemistry

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68
Cited By
3.28
FWCI (Field Weighted Citation Impact)
19
Refs
0.91
Citation Normalized Percentile
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Citation History

Topics

Graphene and Nanomaterials Applications
Physical Sciences →  Engineering →  Biomedical Engineering
Nanoparticle-Based Drug Delivery
Physical Sciences →  Materials Science →  Biomaterials
Nanoplatforms for cancer theranostics
Physical Sciences →  Engineering →  Biomedical Engineering
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