Synthesis of 3,5-Biscarbonyl-1<i>H</i>-1,2,4-Triazole Derivatives

Javier de Mendoza; J. M. ONTORIA; M. Carmen Ortega; Tomás Torres⊗

doi:10.1055/s-1992-26122

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Synthesis of 3,5-Biscarbonyl-1H-1,2,4-Triazole Derivatives

Javier de Mendoza J. M. ONTORIA M. Carmen Ortega Tomás Torres⊗

Year: 1992 Journal: Synthesis Vol: 1992 (04)Pages: 398-402 Publisher: Thieme Medical Publishers (Germany)

DOI: 10.1055/s-1992-26122

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Abstract

The hitherto unreported 1H-1,2,4-triazole-3,5-dicarbaldehyde can be prepared in three steps by condensation of methyl dimethoxyacetate with hydrazine, followed by oxidative deamination and deacetalization.

Keywords:

Chemistry Hydrazine (antidepressant) 1,2,4-Triazole Oxidative deamination Triazole Deamination Condensation Medicinal chemistry Organic chemistry Stereochemistry

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Synthesis and Characterization of Heterocyclic Compounds

Physical Sciences → Chemistry → Organic Chemistry

Click Chemistry and Applications

Physical Sciences → Chemistry → Organic Chemistry

Synthesis and Biological Evaluation

Physical Sciences → Chemistry → Organic Chemistry

Synthesis of 3,5-Biscarbonyl-1H-1,2,4-Triazole Derivatives

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