Lithium improves HIV-associated neurocognitive impairment

Scott Letendre; Steven Paul Woods; Ronald J. Ellis; J. Hampton Atkinson; Eliezer Masliah; Geoffrey van den Brande; Janis Durelle; Igor Grant; Ian Everall

doi:10.1097/01.aids.0000244208.49123.1b

JOURNAL ARTICLE

Lithium improves HIV-associated neurocognitive impairment

Scott Letendre Steven Paul Woods Ronald J. Ellis J. Hampton Atkinson Eliezer Masliah Geoffrey van den Brande Janis Durelle Igor Grant Ian Everall

Year: 2006 Journal: AIDS Vol: 20 (14)Pages: 1885-1888 Publisher: Lippincott Williams & Wilkins

DOI: 10.1097/01.aids.0000244208.49123.1b

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Abstract

Lithium resulted in improved neuropsychological performance in antiretroviral-treated, impaired individuals in this small, open-label study. Based on published in vitro data, lithium may exert this effect by inhibiting neuronal glycogen synthase kinase-3beta.

Keywords:

Neurocognitive Adverse effect Medicine Lithium (medication) Neuropsychology Internal medicine Psychiatry Cognition

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Topics

HIV Research and Treatment

Life Sciences → Immunology and Microbiology → Virology

Bipolar Disorder and Treatment

Health Sciences → Medicine → Psychiatry and Mental health

Genetics and Neurodevelopmental Disorders

Life Sciences → Biochemistry, Genetics and Molecular Biology → Genetics

Lithium improves HIV-associated neurocognitive impairment

Abstract

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Citation History

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