Synthesis and Biological Activity of Bactobolin Glucosides

Hayamitsu Adachi; Yoshio Nishimura

doi:10.1080/1057563021000060112

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JOURNAL ARTICLE

Synthesis and Biological Activity of Bactobolin Glucosides

Hayamitsu Adachi Yoshio Nishimura

Year: 2003 Journal: Natural Product Research Vol: 17 (4)Pages: 253-257 Publisher: Taylor & Francis

DOI: 10.1080/1057563021000060112

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Abstract

Bactobolin glucosides, 5-O-(alpha-D-glucopyranosyl)-, 5-O-(beta-D-glucopyranosyl)- and 6-O-(beta-D-glucopyranosyl)-bactobolin were prepared by glycosidation of bactobolin (1) with the glucopyranosyl trichloroacetoimidate. These compounds were evaluated antimicrobial activity and cytotoxicity.

Keywords:

Antimicrobial Cytotoxicity Chemistry Stereochemistry Glucoside Biological activity Traditional medicine Organic chemistry Biochemistry In vitro Medicine

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Plant biochemistry and biosynthesis

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Synthetic Organic Chemistry Methods

Physical Sciences → Chemistry → Organic Chemistry

Natural product bioactivities and synthesis

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Synthesis and Biological Activity of Bactobolin Glucosides

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