A convenient and versatile synthesis of 4‐trifluoromethyl‐substituted pyrazoles

Giovanni Meazza; G. Zanardi; P. Piccardi

doi:10.1002/jhet.5570300213

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A convenient and versatile synthesis of 4‐trifluoromethyl‐substituted pyrazoles

Giovanni Meazza G. Zanardi P. Piccardi

Year: 1993 Journal: Journal of Heterocyclic Chemistry Vol: 30 (2)Pages: 365-371 Publisher: Wiley

DOI: 10.1002/jhet.5570300213

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Abstract

Abstract Trifluoromethyl‐substituted pyrazoles were synthesized via 1,3‐dipolar cycloaddition from sydnones 2a‐j and 1‐aryl‐3,3,3‐trifluoro‐propynes 5a‐f. The regioselectivity of the reaction and the spectroscopic characteristics of the products are discussed.

Keywords:

Chemistry Trifluoromethyl Combinatorial chemistry Organic chemistry

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A convenient and versatile synthesis of 4‐trifluoromethyl‐substituted pyrazoles

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