Y.-J. Oh and K.-H. Jeong report the enhancement of surface-enhanced Raman scattering (SERS) using glass nanopillars surrounded by nanogap-rich silver nanoislands at wafer level. On page 2234, they explain how high-density hot spots are generated by increasing the number of nanogap-rich nanoislands within a detection volume. The SERS substrate shows high enhancement factor with excellent signal uniformity. This novel substrate enables the label-free detection of aqueous DNA base molecules at nanomolar level.
M. ParkYoungJae OhKi‐Hun Jeong
Yunfang ZhangDeng YubinHan LiuLong‐Biao HuangXin DingZhiyong BaiChangrui LiaoYiping WangYing Wang
Zhenxina LiThang Duy DaoTadaaki NagaoMotoki TeranoMasahiko Yoshino
Joshua D. CaldwellO. J. GlembockiFrancisco J. BezaresNabil BassimR. W. RendellMariya FeygelsonMaraizu UkaegbuRichard KasicaLoretta ShireyCharles M. Hosten