Is the rest perfusion measurement necessary for the diagnosis of myocardial ischaemia in quantitative cardiac perfusion? A CE-MARC sub-study

Abstract

Background Diagnostic studies using dynamic contrast enhanced (DCE) MRI perfusion imaging typically evaluate perfusion in terms of the myocardial perfusion reserve (MPR), which is the ratio of stress to rest myocardial blood flow (MBF) measurements. The aim of this study was to establish whether or not, in the case of absolute MBF quantitation, the MPR exhibits a diagnostic advantage over the stress MBF measurements alone.