JOURNAL ARTICLE

Segmental and dynamic intensity‐modulated radiotherapy delivery techniques for micro‐multileaf collimator

Nzhde AgazaryanTimothy D. Solberg

Year: 2003 Journal:   Medical Physics Vol: 30 (7)Pages: 1758-1767   Publisher: Wiley

Abstract

A leaf sequencing algorithm has been implemented to deliver segmental and dynamic multileaf collimated intensity‐modulated radiotherapy (SMLC–IMRT and DMLC–IMRT, respectively) using a linear accelerator equipped with a micro‐multileaf collimator (mMLC). The implementation extends a previously published algorithm for the SMLC–IMRT to include the dynamic MLC–IMRT method and several dosimetric considerations. The algorithm has been extended to account for the transmitted radiation and minimize the leakage between opposing and neighboring leaves. The underdosage problem associated with the tongue‐and‐groove design of the MLC is significantly reduced by synchronizing the MLC leaf movements. The workings of the leaf sequencing parameters have been investigated and the results of the planar dosimetric investigations show that the sequencing parameters affect the measured dose distributions as intended. Investigations of clinical cases suggest that SMLC and DMLC delivery methods produce comparable results with leaf sequences obtained by root‐mean‐square (RMS) errors specification of 1.5% and lower, approximately corresponding to 20 or more segments. For SMLC–IMRT, there is little to be gained by using an RMS error specification smaller than 2%, approximately corresponding to 15 segments; however, more segments directly translate to longer treatment time and more strain on the MLC. The implemented leaf synchronization method does not increase the required monitor units while it reduces the measured TG underdoses from a maximum of 12% to a maximum of 3% observed with single field measurements of representative clinical cases studied.

Keywords:
Multileaf collimator Collimated light Intensity modulation Synchronizing Collimator Dosimetry Linear particle accelerator Nuclear medicine Computer science Biomedical engineering Algorithm Medicine Optics Physics Beam (structure) Transmission (telecommunications)

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Citation History

Topics

Advanced Radiotherapy Techniques
Physical Sciences →  Physics and Astronomy →  Radiation
Radiation Therapy and Dosimetry
Health Sciences →  Medicine →  Pulmonary and Respiratory Medicine
Microfluidic and Capillary Electrophoresis Applications
Physical Sciences →  Engineering →  Biomedical Engineering
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