JOURNAL ARTICLE
154 POSTER Novel produrugs of SN38 generated by Multi-Arm Poly(ethylene glycol)
Hongyong ZhaoBelen RubioZ. ZhangClifford LongleyPuja SapraDianguo WuPrakash SaiC D ConoverLee M. GreenbergerIvan D. Horak
Year: 2006 Journal: European Journal of Cancer Supplements Vol: 4 (12)Pages: 50-50 Publisher: Elsevier BV
Keywords:
Camptothecin SN-38 High-performance liquid chromatography Irinotecan Chemistry Ethylene glycol Active metabolite Combinatorial chemistry Metabolite Carboxylate Prodrug Lactone PEG ratio Chromatography Stereochemistry Organic chemistry Biochemistry Cancer Biology
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Topics
Cancer therapeutics and mechanisms
Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology
Cancer Treatment and Pharmacology
Health Sciences → Medicine → Oncology
Synthesis and Biological Evaluation
Physical Sciences → Chemistry → Organic Chemistry
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