JOURNAL ARTICLE

Preparation and Evaluation of Nano-Hydroxyapatite/β-Tricalcium Phosphate/Chitosan Composite Scaffolds for Bone Tissue Engineering

Tiezhu LinS.M. ZhangJunsheng LiLianke ZhangY.H. LiuYawen Xue

Year: 2007 Journal:   Key engineering materials Vol: 361-363 Pages: 463-466   Publisher: Trans Tech Publications

Abstract

The composite scaffolds with nine different ratios of nano-HA and ß-TCP content were fabricated by using lyophilization method. Their microscopy, physical and chemical properties were investigated by using scanning electron microscopy (SEM), X-ray diffraction (XRD), and fourier transformed infrared (FTIR) spectroscopy. MTT test was applied to quantitatively assess the number of viable cells attached and grown on the scaffolds. And the result showed that the amount of cells on the scaffold containing 30% by mass of nano-HA was significantly higher than the other samples.

Keywords:
Fourier transform infrared spectroscopy Scanning electron microscope Chitosan Composite number Materials science Nano- Scaffold Chemical engineering Tissue engineering Biomedical engineering Nuclear chemistry Composite material Chemistry

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Topics

Bone Tissue Engineering Materials
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