Solvent‐Free Passerini Reactions

Dominik Koszelewski; Wiktor Szymański; Joanna Krysiak; Ryszard Ostaszewski

doi:10.1080/00397910701863608

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JOURNAL ARTICLE

Solvent‐Free Passerini Reactions

Dominik Koszelewski Wiktor Szymański Joanna Krysiak Ryszard Ostaszewski

Year: 2008 Journal: Synthetic Communications Vol: 38 (7)Pages: 1120-1127 Publisher: Taylor & Francis

DOI: 10.1080/00397910701863608

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Abstract

The influence of the substrate structure and concentration on the yield of the Passerini reaction was studied. A new, solvent-free methodology for a convenient preparation of alpha-acyloxyamides 4 was established and compared to the classical methodology. A higher reaction yield was obtained in shorter time, especially in the case of aromatic aldehydes.

Keywords:

Chemistry Yield (engineering) Solvent Substrate (aquarium) Organic chemistry Reaction conditions Catalysis Metallurgy

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Solvent‐Free Passerini Reactions

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