Dendronized Gold Nanoparticles for siRNA Delivery

Sung Tae Kim; Apiwat Chompoosor; Yi‐Cheun Yeh; Sarit S. Agasti; David J. Solfiell; Vincent M. Rotello

doi:10.1002/smll.201201141

ScienceGate Book Chapters

JOURNAL ARTICLE

Dendronized Gold Nanoparticles for siRNA Delivery

Sung Tae Kim Apiwat Chompoosor Yi‐Cheun Yeh Sarit S. Agasti David J. Solfiell Vincent M. Rotello

Year: 2012 Journal: Small Vol: 8 (21)Pages: 3253-3256 Publisher: Wiley

DOI: 10.1002/smll.201201141

Get Full-Text PDF Get Analytical Report

Abstract

Dendronized gold nanoparticles (AuNPs) are effective nanocarriers for small interfering RNA (siRNA) delivery. Electrostatic condension of these AuNPs with siRNA provides efficient silencing (∼50%) without cytotoxicity.

Keywords:

Nanoparticle Nanotechnology Colloidal gold Materials science

Metrics

114

Cited By

5.47

FWCI (Field Weighted Citation Impact)

Refs

0.96

Citation Normalized Percentile

Is in top 1%

Is in top 10%

Citation History

Topics

RNA Interference and Gene Delivery

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

Advanced biosensing and bioanalysis techniques

Life Sciences → Biochemistry, Genetics and Molecular Biology → Molecular Biology

MicroRNA in disease regulation

Life Sciences → Biochemistry, Genetics and Molecular Biology → Cancer Research

Dendronized Gold Nanoparticles for siRNA Delivery

Abstract

Metrics

Citation History

Topics

Related Documents

PEGylation of Dendronized Gold Nanoparticles Affects Their Interaction with Thrombin and siRNA

Gold Nanoparticles Capped with Polyethyleneimine for Enhanced siRNA Delivery

Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery

Cyclic Peptide-Capped Gold Nanoparticles for Enhanced siRNA Delivery

Layer-by-Layer Assembled Gold Nanoparticles for siRNA Delivery