JOURNAL ARTICLE

Anticancer studies of the synthesized gold nanoparticles against MCF 7 breast cancer cell lines

M. R. Kamala PriyaPriya Iyer

Year: 2014 Journal:   Applied Nanoscience Vol: 5 (4)Pages: 443-448   Publisher: Springer Science+Business Media

Abstract

It has been previously stated that gold nanoparticles have been successfully synthesized using various green extracts of plants. The synthesized gold nanoparticles were characterized under scanning electron microscopy and EDX to identify the size of the nanoparticles. It was found that the nanoparticles were around 30 nm in size, which is a commendable nano dimension achieved through a plant mediated synthesis. The nanoparticles were further studied for their various applications. In the current study, we have made attempts to exploit the anticancer ability of the gold nano particles. The nanoparticles were studied against MCF 7 breast cancer cell lines. The results obtained from the studies of anticancer activity showed that gold nanoparticles gave an equivalent good results, in par with the standard drugs against cancer. The AuNP's proved to be efficient even from the minimum concentrations of 2 μg/ml, and as the concentration increased the anticancer efficacy as well increased.

Keywords:
MCF-7 Nanochemistry Colloidal gold Nanoparticle Nanotechnology Materials science Cancer cell lines Cancer cell Breast cancer Cancer Nuclear chemistry Chemistry Human breast Medicine Internal medicine

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0.84
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Citation History

Topics

Nanoparticles: synthesis and applications
Physical Sciences →  Materials Science →  Materials Chemistry
Nanoparticle-Based Drug Delivery
Physical Sciences →  Materials Science →  Biomaterials
Graphene and Nanomaterials Applications
Physical Sciences →  Engineering →  Biomedical Engineering
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